产品货号：
Z19443
中文名称：
Kallikrein 6/KLK6抗体
英文名称：
Anti-Kallikrein 6/KLK6 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Kallikrein 6/KLK6 Antibody |
| 指标别名 | kallikrein related peptidase 6;Bssp;Klk7;PRSS18;PRSS9;SP59;hK6;KLK6 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,ELISA |
| 基因名称 | KLK6 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Kallikrein 6 recombinant protein (Position:L22-K244). |
| 实际分子量 | 29KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | KLK6(Kallikrein-related peptidase 6),also called KALLIKREIN 6,NEUROSIN,PROTEASE M,ZYME or PRSS9,is a protein that in humans is encoded by the KLK6 gene.This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19.The encoded enzyme is regulated by steroid hormones.Northern blot analysis revealed that the PRSS9 mRNA was expressed in several primary tumors and cell lines from mammary,prostate,and ovarian cancers,but was not detected in any metastases of these cancers.The KLK6 gene is mapped on 19q13.41.In tissue culture,the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein,suggesting a potential for involvement in Alzheimer's disease.Upon cellular stress,neurosin was released from mitochondria to the cytosol,which resulted in the increase of degraded alpha-synuclein species.Neurosin may play a significant role in physiologic alpha-synuclein degradation and also in the pathogenesis of synucleinopathies. |
| Uniprot ID | Q92876 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 ELISA： 1:100～1000 |
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